Hepatitis C Virus (HCV) Occult Infection or Occult HCV RNA Detection?
نویسندگان
چکیده
منابع مشابه
Detection of hepatitis C virus (HCV) core-specific antibody suggests occult HCV infection among blood donors.
BACKGROUND Blood transfusion safety is based on reliable donor screening for transmissible infections such as the hepatitis C virus (HCV) infection. STUDY DESIGN AND METHODS A novel HCV core-specific antibody was assayed on random single donations from 2007 first-time blood donors who tested negative for anti-HCV and HCV RNA on routine screening. Sample collection broke the code between donat...
متن کاملCombined hepatitis C virus (HCV) antigen-antibody detection assay does not improve diagnosis for seronegative individuals with occult HCV infection.
A combined hepatitis C virus (HCV) antigen-antibody assay was evaluated for 115 seronegative individuals with occult HCV infection. The assay was reactive in one patient and negative to weakly reactive in three others (all four gave indeterminate results by supplemental assay) but failed to detect HCV in the remaining patients. Despite increased sensitivity the combined assay does not improve s...
متن کاملDoes occult hepatitis C virus infection exist?
Occult hepatitis C virus (HCV) infection has been found in anti-HCV and serum HCV RNA-negative patients with abnormal results of liver function tests of unknown origin and in patients with spontaneous or treatment-induced recovery from hepatitis C (2–6, 9–11). In a recent issue of the Journal of Clinical Microbiology, Halfon and coworkers questioned the existence of occult HCV infection as they...
متن کاملHepatitis B virus genotype, HBsAg mutations and co-infection with HCV in occult HBV infection.
BACKGROUND The association between mutations in the hepatitis B surface antigen (HBsAg) gene and the occurrence of occult HBV (OBI) in patients has not been studied adequately to determine if the two are correlated. The current study was aimed to investigate HBsAg mutations, the genotype of HBV and co-infection with HCV in OBI in the central part of Iran to determine any possible associations. ...
متن کاملCHARACTERISTICS AND PREVALENCE OF OCCULT HEPATITIS B VIRUS INFECTION IN PATIENTS WITH HEPATITIS C IN IRAN
ABSTRACT Background: Hepatitis B virus (HBV) infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection. Such infections have been frequently identified in patients with chronic hepatitis Cliver disease, but their prevalence is not known. Methods: 207 patients with chronic hepatitis C who were HCV -RNA and antiHCV positive were stu...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2004
ISSN: 0022-1899,1537-6613
DOI: 10.1086/380203